3vqs

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File:3vqs.jpg

Template:STRUCTURE 3vqs

Crystal structure of HCV NS5B RNA polymerase with a novel piperazine inhibitorCrystal structure of HCV NS5B RNA polymerase with a novel piperazine inhibitor

Template:ABSTRACT PUBMED 22615294

About this StructureAbout this Structure

3vqs is a 4 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Ando I, Adachi T, Ogura N, Toyonaga Y, Sugimoto K, Abe H, Kamada M, Noguchi T. Preclinical Characterization of JTK-853, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase. Antimicrob Agents Chemother. 2012 Aug;56(8):4250-6. Epub 2012 May 21. PMID:22615294 doi:10.1128/AAC.00312-12

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OCA