3f5x

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Template:STRUCTURE 3f5x

File:3f5x.png

CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active siteCDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site

Template:ABSTRACT PUBMED 19097791

About this StructureAbout this Structure

3f5x is a 4 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Trujillo JI, Kiefer JR, Huang W, Thorarensen A, Xing L, Caspers NL, Day JE, Mathis KJ, Kretzmer KK, Reitz BA, Weinberg RA, Stegeman RA, Wrightstone A, Christine L, Compton R, Li X. 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor. Bioorg Med Chem Lett. 2009 Feb 1;19(3):908-11. Epub 2008 Dec 6. PMID:19097791 doi:10.1016/j.bmcl.2008.11.105

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