3nww
P38 Alpha kinase complexed with a 2-aminothiazol-5-yl-pyrimidine based inhibitorP38 Alpha kinase complexed with a 2-aminothiazol-5-yl-pyrimidine based inhibitor
Template:ABSTRACT PUBMED 20732813
About this StructureAbout this Structure
3nww is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
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ReferenceReference
- ↑ Lin S, Wrobleski ST, Hynes J Jr, Pitt S, Zhang R, Fan Y, Doweyko AM, Kish KF, Sack JS, Malley MF, Kiefer SE, Newitt JA, McKinnon M, Trzaskos J, Barrish JC, Dodd JH, Schieven GL, Leftheris K. Utilization of a nitrogen-sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38alpha MAP kinase inhibitors. Bioorg Med Chem Lett. 2010 Jul 30. PMID:20732813 doi:10.1016/j.bmcl.2010.07.102