4a6l
beta-tryptase inhibitorbeta-tryptase inhibitor
Template:ABSTRACT PUBMED 22192588
About this StructureAbout this Structure
4a6l is a 4 chain structure of Tryptase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Liang G, Aldous S, Merriman G, Levell J, Pribish J, Cairns J, Chen X, Maignan S, Mathieu M, Tsay J, Sides K, Rebello S, Whitely B, Morize I, Pauls HW. Structure-based library design and the discovery of a potent and selective mast cell beta-tryptase inhibitor as an oral therapeutic agent. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1049-54. Epub 2011 Dec 7. PMID:22192588 doi:10.1016/j.bmcl.2011.11.119