2iwx
ANALOGUES OF RADICICOL BOUND TO THE ATP-BINDING SITE OF HSP90.ANALOGUES OF RADICICOL BOUND TO THE ATP-BINDING SITE OF HSP90.
About this StructureAbout this Structure
2iwx is a 1 chain structure of Heat Shock Proteins with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
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ReferenceReference
- ↑ Proisy N, Sharp SY, Boxall K, Connelly S, Roe SM, Prodromou C, Slawin AM, Pearl LH, Workman P, Moody CJ. Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol. Chem Biol. 2006 Nov;13(11):1203-15. PMID:17114002 doi:10.1016/j.chembiol.2006.09.015