Template:STRUCTURE 2iwx

File:2iwx.png

ANALOGUES OF RADICICOL BOUND TO THE ATP-BINDING SITE OF HSP90.ANALOGUES OF RADICICOL BOUND TO THE ATP-BINDING SITE OF HSP90.

Template:ABSTRACT PUBMED 17114002

About this StructureAbout this Structure

2iwx is a 1 chain structure of Heat Shock Proteins with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Proisy N, Sharp SY, Boxall K, Connelly S, Roe SM, Prodromou C, Slawin AM, Pearl LH, Workman P, Moody CJ. Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol. Chem Biol. 2006 Nov;13(11):1203-15. PMID:17114002 doi:10.1016/j.chembiol.2006.09.015

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