3roc
Crystal structure of human p38 alpha complexed with a pyrimidinone compoundCrystal structure of human p38 alpha complexed with a pyrimidinone compound
Template:ABSTRACT PUBMED 21620699
About this StructureAbout this Structure
3roc is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Devadas B, Selness SR, Xing L, Madsen HM, Marrufo LD, Shieh H, Messing DM, Yang JZ, Morgan HM, Anderson GD, Webb EG, Zhang J, Devraj RV, Monahan JB. Substituted N-aryl-6-pyrimidinones: A new class of potent, selective, and orally active p38 MAP kinase inhibitors. Bioorg Med Chem Lett. 2011 Jul 1;21(13):3856-60. Epub 2011 May 8. PMID:21620699 doi:10.1016/j.bmcl.2011.05.006