2jg4

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Template:STRUCTURE 2jg4

File:2jg4.png

SUBSTRATE-FREE IDE STRUCTURE IN ITS CLOSED CONFORMATIONSUBSTRATE-FREE IDE STRUCTURE IN ITS CLOSED CONFORMATION

Template:ABSTRACT PUBMED 17613531

About this StructureAbout this Structure

2jg4 is a 2 chain structure of Insulin-Degrading Enzyme with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Im H, Manolopoulou M, Malito E, Shen Y, Zhao J, Neant-Fery M, Sun CY, Meredith SC, Sisodia SS, Leissring MA, Tang WJ. Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE. J Biol Chem. 2007 Aug 31;282(35):25453-63. Epub 2007 Jul 5. PMID:17613531 doi:10.1074/jbc.M701590200

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