3cjf
Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidineCrystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine
Template:ABSTRACT PUBMED 18620382
About this StructureAbout this Structure
3cjf is a 1 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Harris PA, Boloor A, Cheung M, Kumar R, Crosby RM, Davis-Ward RG, Epperly AH, Hinkle KW, Hunter RN 3rd, Johnson JH, Knick VB, Laudeman CP, Luttrell DK, Mook RA, Nolte RT, Rudolph SK, Szewczyk JR, Truesdale AT, Veal JM, Wang L, Stafford JA. Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-m ethyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. J Med Chem. 2008 Aug 14;51(15):4632-40. Epub 2008 Jul 12. PMID:18620382 doi:10.1021/jm800566m
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Nolte, R T.
- Angiogenesis
- Atp-binding
- Developmental protein
- Differentiation
- Glycoprotein
- Host-virus interaction
- Immunoglobulin domain
- Kinase insert domain receptor
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Protein-tyrosine kinase receptor flk-1
- Transferase
- Transmembrane
- Tyrosine-protein kinase
- Vascular endothelial growth factor receptor 2. vegfr-2