Template:STRUCTURE 3b28

File:3b28.png

Hsp90 alpha N-terminal domain in complex with an inhibitor CH5015765Hsp90 alpha N-terminal domain in complex with an inhibitor CH5015765

Template:ABSTRACT PUBMED 21875802

About this StructureAbout this Structure

3b28 is a 2 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Miura T, Fukami TA, Hasegawa K, Ono N, Suda A, Shindo H, Yoon DO, Kim SJ, Na YJ, Aoki Y, Shimma N, Tsukuda T, Shiratori Y. Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5778-83. Epub 2011 Aug 6. PMID:21875802 doi:10.1016/j.bmcl.2011.08.001

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OCA