1i5r

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File:1i5r.png

Template:STRUCTURE 1i5r

TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EM1745 COMPLEXTYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EM1745 COMPLEX

Template:ABSTRACT PUBMED 12223444

About this StructureAbout this Structure

1i5r is a 1 chain structure of Hydroxysteroid dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Qiu W, Campbell RL, Gangloff A, Dupuis P, Boivin RP, Tremblay MR, Poirier D, Lin SX. A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity. FASEB J. 2002 Nov;16(13):1829-31. Epub 2002 Sep 5. PMID:12223444 doi:10.1096/fj.02-0026fje
  2. ↑ Schuster D, Nashev LG, Kirchmair J, Laggner C, Wolber G, Langer T, Odermatt A. Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries. J Med Chem. 2008 Jul 24;51(14):4188-99. Epub 2008 Jun 6. PMID:18533708 doi:10.1021/jm800054h

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