3jwq
Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafilCrystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafil
Template:ABSTRACT PUBMED 19798052
About this StructureAbout this Structure
3jwq is a 4 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Barren B, Gakhar L, Muradov H, Boyd KK, Ramaswamy S, Artemyev NO. Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit. EMBO J. 2009 Nov 18;28(22):3613-22. Epub 2009 Oct 1. PMID:19798052 doi:10.1038/emboj.2009.284
- ↑ Goc A, Chami M, Lodowski DT, Bosshart P, Moiseenkova-Bell V, Baehr W, Engel A, Palczewski K. Structural characterization of the rod cGMP phosphodiesterase 6. J Mol Biol. 2010 Aug 20;401(3):363-73. Epub 2010 Jul 1. PMID:20600113 doi:10.1016/j.jmb.2010.06.044
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OCACategories:
- Pages with broken file links
- 3',5'-cyclic-GMP phosphodiesterase
- Homo sapiens
- Artemyev, N O.
- Barren, B.
- Boyd, K K.
- Gakhar, L.
- Muradov, H.
- Ramaswamy, S.
- Allosteric enzyme
- Cell membrane
- Cgmp
- Cgmp-binding
- Hydrolase
- Lipoprotein
- Magnesium
- Membrane
- Metal-binding
- Methylation
- Mostly alpha
- Nucleotide-binding
- Phosphoprotein
- Prenylation
- Sensory transduction
- Vision