1jsu
P27(KIP1)/CYCLIN A/CDK2 COMPLEXP27(KIP1)/CYCLIN A/CDK2 COMPLEX
About this StructureAbout this Structure
1jsu is a 3 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Russo AA, Jeffrey PD, Patten AK, Massague J, Pavletich NP. Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature. 1996 Jul 25;382(6589):325-31. PMID:8684460 doi:10.1038/382325a0
- ↑ Lacy ER, Filippov I, Lewis WS, Otieno S, Xiao L, Weiss S, Hengst L, Kriwacki RW. p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding. Nat Struct Mol Biol. 2004 Apr;11(4):358-64. Epub 2004 Mar 14. PMID:15024385 doi:10.1038/nsmb746