1izh
Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutantsInhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants
About this StructureAbout this Structure
1izh is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Weber J, Mesters JR, Lepsik M, Prejdova J, Svec M, Sponarova J, Mlcochova P, Skalicka K, Strisovsky K, Uhlikova T, Soucek M, Machala L, Stankova M, Vondrasek J, Klimkait T, Kraeusslich HG, Hilgenfeld R, Konvalinka J. Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains. J Mol Biol. 2002 Dec 6;324(4):739-54. PMID:12460574