Template:STRUCTURE 1izh

File:1izh.png

Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutantsInhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants

Template:ABSTRACT PUBMED 12460574

About this StructureAbout this Structure

1izh is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

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ReferenceReference

[xtra 1]

  1. Weber J, Mesters JR, Lepsik M, Prejdova J, Svec M, Sponarova J, Mlcochova P, Skalicka K, Strisovsky K, Uhlikova T, Soucek M, Machala L, Stankova M, Vondrasek J, Klimkait T, Kraeusslich HG, Hilgenfeld R, Konvalinka J. Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains. J Mol Biol. 2002 Dec 6;324(4):739-54. PMID:12460574

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OCA