1cfy

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File:1cfy.gif


1cfy, resolution 2.3Å

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YEAST COFILIN, MONOCLINIC CRYSTAL FORM

OverviewOverview

Cofilin, a ubiquitous 15,000 M(r) protein, plays a central role in regulating cytoskeletal dynamics. Cofilin binds to actin monomers and filaments, and has a pH-dependent actin severing activity. The structure will allow for a detailed analysis of cofilin function.

About this StructureAbout this Structure

1CFY is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

ReferenceReference

Structure determination of yeast cofilin., Fedorov AA, Lappalainen P, Fedorov EV, Drubin DG, Almo SC, Nat Struct Biol. 1997 May;4(5):366-9. PMID:9145106

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