3d5m
Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitorCrystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor
Template:ABSTRACT PUBMED 18554907
About this StructureAbout this Structure
3d5m is a 2 chain structure of RNA polymerase with sequence from Viruses. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Kim SH, Tran MT, Ruebsam F, Xiang AX, Ayida B, McGuire H, Ellis D, Blazel J, Tran CV, Murphy DE, Webber SE, Zhou Y, Shah AM, Tsan M, Showalter RE, Patel R, Gobbi A, LeBrun LA, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L, Zhao Q, Han Q, Kissinger CR. Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4181-5. Epub 2008 May 24. PMID:18554907 doi:10.1016/j.bmcl.2008.05.083