3fr0
Human glucokinase in complex with 2-amino benzamide activatorHuman glucokinase in complex with 2-amino benzamide activator
About this StructureAbout this Structure
3fr0 is a 1 chain structure of Hexokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Nishimura T, Iino T, Mitsuya M, Bamba M, Watanabe H, Tsukahara D, Kamata K, Sasaki K, Ohyama S, Hosaka H, Futamura M, Nagata Y, Eiki J. Identification of novel and potent 2-amino benzamide derivatives as allosteric glucokinase activators. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1357-60. Epub 2009 Jan 21. PMID:19188063 doi:10.1016/j.bmcl.2009.01.053
- ↑ Kamata K, Mitsuya M, Nishimura T, Eiki J, Nagata Y. Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase. Structure. 2004 Mar;12(3):429-38. PMID:15016359 doi:10.1016/j.str.2004.02.005