3n45

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File:3n45.png

Template:STRUCTURE 3n45

Human FPPS complex with FBS_04 and zoledronic acid/MG2+Human FPPS complex with FBS_04 and zoledronic acid/MG2+

Template:ABSTRACT PUBMED 20711197

About this StructureAbout this Structure

3n45 is a 1 chain structure of Farnesyl diphosphate synthase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Jahnke W, Rondeau JM, Cotesta S, Marzinzik A, Pelle X, Geiser M, Strauss A, Gotte M, Bitsch F, Hemmig R, Henry C, Lehmann S, Glickman JF, Roddy TP, Stout SJ, Green JR. Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat Chem Biol. 2010 Sep;6(9):660-6. Epub 2010 Aug 15. PMID:20711197 doi:10.1038/nchembio.421

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