3l3a
Bace-1 with the aminopyridine Compound 32Bace-1 with the aminopyridine Compound 32
About this StructureAbout this Structure
3l3a is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Malamas MS, Barnes K, Hui Y, Johnson M, Lovering F, Condon J, Fobare W, Solvibile W, Turner J, Hu Y, Manas ES, Fan K, Olland A, Chopra R, Bard J, Pangalos MN, Reinhart P, Robichaud AJ. Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2068-73. Epub 2010 Feb 23. PMID:20223661 doi:10.1016/j.bmcl.2010.02.075