2zgx
Thrombin InhibitionThrombin Inhibition
Template:ABSTRACT PUBMED 19520086
About this StructureAbout this Structure
2zgx is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Baum B, Muley L, Heine A, Smolinski M, Hangauer D, Klebe G. Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin. J Mol Biol. 2009 Aug 21;391(3):552-64. Epub 2009 Jun 9. PMID:19520086 doi:10.1016/j.jmb.2009.06.016
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OCACategories:
- Pages with broken file links
- Hirudo medicinalis
- Homo sapiens
- Thrombin
- Baum, B.
- Heine, A.
- Klebe, G.
- Acute phase
- Blood clotting
- Blood coagulation
- Cleavage on pair of basic residue
- Disease mutation
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase inhibitor
- Hydrolase-hydrolase inhibitor complex
- Kringle
- Protease
- Protease inhibitor
- Secreted
- Serine protease
- Serine protease inhibitor
- Sulfation
- Zymogen