3oaw
4-Methylpteridineones as Orally Active and Selective PI3K/mTOR Dual Inhibitors4-Methylpteridineones as Orally Active and Selective PI3K/mTOR Dual Inhibitors
About this StructureAbout this Structure
3oaw is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.
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ReferenceReference
- ↑ Liu KK, Bagrodia S, Bailey S, Cheng H, Chen H, Gao L, Greasley S, Hoffman JE, Hu Q, Johnson TO, Knighton D, Liu Z, Marx MA, Nambu MD, Ninkovic S, Pascual B, Rafidi K, Rodgers CM, Smith GL, Sun S, Wang H, Yang A, Yuan J, Zou A. 4-Methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6096-9. Epub 2010 Aug 14. PMID:20817449 doi:10.1016/j.bmcl.2010.08.045