1dwx
MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER N-HYDROXYARGININE AND TETRAHYDROBIOPTERINMURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER N-HYDROXYARGININE AND TETRAHYDROBIOPTERIN
Template:ABSTRACT PUBMED 10769116
About this StructureAbout this Structure
1dwx is a 2 chain structure of Nitric Oxide Synthase with sequence from Mus musculus. Full crystallographic information is available from OCA.
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ReferenceReference
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- ↑ Crane BR, Arvai AS, Ghosh S, Getzoff ED, Stuehr DJ, Tainer JA. Structures of the N(omega)-hydroxy-L-arginine complex of inducible nitric oxide synthase oxygenase dimer with active and inactive pterins. Biochemistry. 2000 Apr 25;39(16):4608-21. PMID:10769116
- ↑ Crane BR, Rosenfeld RJ, Arvai AS, Ghosh DK, Ghosh S, Tainer JA, Stuehr DJ, Getzoff ED. N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization. EMBO J. 1999 Nov 15;18(22):6271-81. PMID:10562539 doi:http://dx.doi.org/10.1093/emboj/18.22.6271
- ↑ Ghosh DK, Crane BR, Ghosh S, Wolan D, Gachhui R, Crooks C, Presta A, Tainer JA, Getzoff ED, Stuehr DJ. Inducible nitric oxide synthase: role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction. EMBO J. 1999 Nov 15;18(22):6260-70. PMID:10562538 doi:http://dx.doi.org/10.1093/emboj/18.22.6260
- ↑ Crane BR, Arvai AS, Ghosh DK, Wu C, Getzoff ED, Stuehr DJ, Tainer JA. Structure of nitric oxide synthase oxygenase dimer with pterin and substrate. Science. 1998 Mar 27;279(5359):2121-6. PMID:9516116
- ↑ Crane BR, Arvai AS, Gachhui R, Wu C, Ghosh DK, Getzoff ED, Stuehr DJ, Tainer JA. The structure of nitric oxide synthase oxygenase domain and inhibitor complexes. Science. 1997 Oct 17;278(5337):425-31. PMID:9334294
- ↑ Wang ZQ, Wei CC, Sharma M, Pant K, Crane BR, Stuehr DJ. A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles. J Biol Chem. 2004 Apr 30;279(18):19018-25. Epub 2004 Feb 19. PMID:14976216 doi:10.1074/jbc.M311663200
- ↑ Kabir M, Sudhamsu J, Crane BR, Yeh SR, Rousseau DL. Substrate-ligand interactions in Geobacillus stearothermophilus nitric oxide synthase. Biochemistry. 2008 Nov 25;47(47):12389-97. PMID:18956884 doi:10.1021/bi801491e