2qe5

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File:2qe5.png

Template:STRUCTURE 2qe5

Structure of HCV NS5B Bound to an Anthranilic Acid InhibitorStructure of HCV NS5B Bound to an Anthranilic Acid Inhibitor

Template:ABSTRACT PUBMED 17402724

About this StructureAbout this Structure

2qe5 is a 4 chain structure of RNA polymerase with sequence from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Nittoli T, Curran K, Insaf S, DiGrandi M, Orlowski M, Chopra R, Agarwal A, Howe AY, Prashad A, Floyd MB, Johnson B, Sutherland A, Wheless K, Feld B, O'Connell J, Mansour TS, Bloom J. Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase. J Med Chem. 2007 May 3;50(9):2108-16. Epub 2007 Apr 3. PMID:17402724 doi:10.1021/jm061428x

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