4dhf

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File:4dhf.jpg

Template:STRUCTURE 4dhf

Structure of Aurora A mutant bound to Biogenidec cpd 15Structure of Aurora A mutant bound to Biogenidec cpd 15

Template:ABSTRACT PUBMED 22607669

About this StructureAbout this Structure

4dhf is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Le Brazidec JY, Pasis A, Tam B, Boykin C, Wang D, Marcotte DJ, Claassen G, Chong JH, Chao J, Fan J, Nguyen K, Silvian L, Ling L, Zhang L, Choi M, Teng M, Pathan N, Zhao S, Li T, Taveras A. Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4033-7. Epub 2012 Apr 25. PMID:22607669 doi:10.1016/j.bmcl.2012.04.085

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