4anx

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File:4anx.png

Template:STRUCTURE 4anx

Complexes of PI3Kgamma with isoform selective inhibitors.Complexes of PI3Kgamma with isoform selective inhibitors.

Template:ABSTRACT PUBMED 22548342

About this StructureAbout this Structure

4anx is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Leahy JW, Buhr CA, Johnson HW, Kim BG, Baik T, Cannoy J, Forsyth TP, Jeong JW, Lee MS, Ma S, Noson K, Wang L, Williams M, Nuss JM, Brooks E, Foster P, Goon L, Heald N, Holst C, Jaeger C, Lam S, Lougheed J, Nguyen L, Plonowski A, Song J, Stout T, Wu X, Yakes MF, Yu P, Zhang W, Lamb P, Raeber O. Discovery of a Novel Series of Potent and Orally Bioavailable Phosphoinositide 3-Kinase gamma Inhibitors. J Med Chem. 2012 May 17. PMID:22548342 doi:10.1021/jm300403a

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