4dt6

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File:4dt6.png

Template:STRUCTURE 4dt6

Co-crystal structure of eIF4E with inhibitorCo-crystal structure of eIF4E with inhibitor

Template:ABSTRACT PUBMED 22458568

About this StructureAbout this Structure

4dt6 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Chen X, Kopecky D, Mihalic J, Jeffries S, Min X, Heath J, Deignan J, Sujen L, Fu Z, Guimaraes C, Li S, Johnstone S, Xu H, Cardozo M, Shen W, Walker N, Kayser F, Wang Z. Structure-guided design, synthesis and evaluation of guanine-derived inhibitors of the eIF4E mRNA-cap interaction. J Med Chem. 2012 Mar 29. PMID:22458568 doi:10.1021/jm300037x

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