3b8q
Crystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitorCrystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitor
Template:ABSTRACT PUBMED 18324761
About this StructureAbout this Structure
3b8q is a 2 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, Demelfi T, Dipietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Martin MW, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Wang L, White RD, Whittington DA, Zanon R. Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation. J Med Chem. 2008 Mar 27;51(6):1649-67. Epub 2008 Mar 7. PMID:18324761 doi:10.1021/jm701097z
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Gu, Y.
- Long, A M.
- Whittington, D A.
- Zhao, H.
- Angiogenesis
- Atp-binding
- Developmental protein
- Differentiation
- Glycoprotein
- Host-virus interaction
- Immunoglobulin domain
- Membrane
- Nucleotide-binding
- Phosphorylation
- Receptor tyrosine kinase
- Transferase
- Transmembrane
- Tyrosine-protein kinase