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3cjf

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Template:STRUCTURE 3cjf

File:3cjf.png

Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidineCrystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine

Template:ABSTRACT PUBMED 18620382

About this StructureAbout this Structure

3cjf is a 1 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Harris PA, Boloor A, Cheung M, Kumar R, Crosby RM, Davis-Ward RG, Epperly AH, Hinkle KW, Hunter RN 3rd, Johnson JH, Knick VB, Laudeman CP, Luttrell DK, Mook RA, Nolte RT, Rudolph SK, Szewczyk JR, Truesdale AT, Veal JM, Wang L, Stafford JA. Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-m ethyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. J Med Chem. 2008 Aug 14;51(15):4632-40. Epub 2008 Jul 12. PMID:18620382 doi:10.1021/jm800566m

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