2q6b

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Template:STRUCTURE 2q6b

File:2q6b.png

Design and synthesis of novel, conformationally restricted HMG-COA reductase inhibitorsDesign and synthesis of novel, conformationally restricted HMG-COA reductase inhibitors

Template:ABSTRACT PUBMED 17574411

About this StructureAbout this Structure

2q6b is a 4 chain structure of HMG-CoA Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Pfefferkorn JA, Choi C, Song Y, Trivedi BK, Larsen SD, Askew V, Dillon L, Hanselman JC, Lin Z, Lu G, Robertson A, Sekerke C, Auerbach B, Pavlovsky A, Harris MS, Bainbridge G, Caspers N. Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4531-7. Epub 2007 Jun 6. PMID:17574411 doi:10.1016/j.bmcl.2007.05.097

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