3hd3

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File:3hd3.png

Template:STRUCTURE 3hd3

High resolution crystal structure of cruzain bound to the vinyl sulfone inhibitor SMDC-256047High resolution crystal structure of cruzain bound to the vinyl sulfone inhibitor SMDC-256047

Template:ABSTRACT PUBMED 19773167

About this StructureAbout this Structure

3hd3 is a 2 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Bryant C, Kerr ID, Debnath M, Ang KK, Ratnam J, Ferreira RS, Jaishankar P, Zhao D, Arkin MR, McKerrow JH, Brinen LS, Renslo AR. Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6218-21. Epub 2009 Sep 3. PMID:19773167 doi:10.1016/j.bmcl.2009.08.098

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