1ms1

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File:1ms1.png

Template:STRUCTURE 1ms1

Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)

Template:ABSTRACT PUBMED 12419220

About this StructureAbout this Structure

1ms1 is a 2 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Buschiazzo A, Amaya MF, Cremona ML, Frasch AC, Alzari PM. The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis. Mol Cell. 2002 Oct;10(4):757-68. PMID:12419220
  2. ↑ Demir O, Roitberg AE. Modulation of catalytic function by differential plasticity of the active site: case study of Trypanosoma cruzi trans-sialidase and Trypanosoma rangeli sialidase. Biochemistry. 2009 Apr 21;48(15):3398-406. PMID:19216574 doi:10.1021/bi802230y

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