3tyq

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File:3tyq.png

Template:STRUCTURE 3tyq

SAR development and discovery of potent indole-based inhibitors of the hepatitis c virus NS5B polymeraseSAR development and discovery of potent indole-based inhibitors of the hepatitis c virus NS5B polymerase

Template:ABSTRACT PUBMED 22247956

About this StructureAbout this Structure

3tyq is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Chen KX, Lesburg CA, Vibulbhan B, Yang W, Chan TY, Venkatraman S, Velazquez F, Zeng Q, Bennett F, Anilkumar GN, Duca J, Jiang Y, Pinto P, Wang L, Huang Y, Selyutin O, Gavalas S, Pu H, Agrawal S, Feld B, Huang HC, Li C, Cheng KC, Shih NY, Kozlowski JA, Rosenblum SB, Njoroge FG. A Novel Class of Highly Potent Irreversible Hepatitis C Virus (HCV) NS5B Polymerase Inhibitors. J Med Chem. 2012 Jan 16. PMID:22247956 doi:10.1021/jm201322r

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OCA