2pc5

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Revision as of 09:20, 13 February 2008 by OCA (talk | contribs) (New page: left|200px<br /><applet load="2pc5" size="350" color="white" frame="true" align="right" spinBox="true" caption="2pc5, resolution 2.20Å" /> '''Native crystal struc...)
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File:2pc5.jpg


2pc5, resolution 2.20Å

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Native crystal structure analysis on Arabidopsis dUTPase

OverviewOverview

The deoxyuridine triphosphate nucleotidohydrolase gene from Arabidopsis, thaliana was expressed and the gene product was purified. Crystallization, was performed by the hanging-drop vapour-diffusion method at 298 K using 2, M ammonium sulfate as the precipitant. X-ray diffraction data were, collected to 2.2 A resolution using Cu K alpha radiation. The crystal, belongs to the orthorhombic space group P2(1)2(1)2(1), with unit-cell, parameters a = 69.90, b = 70.86 A, c = 75.55 A. Assuming the presence of a, trimer in the asymmetric unit, the solvent content was 30%, with a V(M) of, 1.8 A3 Da(-1).

About this StructureAbout this Structure

2PC5 is a Single protein structure of sequence from Arabidopsis thaliana with as ligand. Active as dUTP diphosphatase, with EC number 3.6.1.23 Known structural/functional Site: . Full crystallographic information is available from OCA.

ReferenceReference

Purification, crystallization and preliminary crystallographic analysis of deoxyuridine triphosphate nucleotidohydrolase from Arabidopsis thaliana., Bajaj M, Moriyama H, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 May 1;63(Pt, 5):409-11. Epub 2007 Apr 14. PMID:17565183

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