Template:STRUCTURE 3ude

File:3ude.jpg

Crystal structure of E. coli HPPK in complex with bisubstrate analogue inhibitor J1BCrystal structure of E. coli HPPK in complex with bisubstrate analogue inhibitor J1B

Template:ABSTRACT PUBMED 22169600

About this StructureAbout this Structure

3ude is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. Shi G, Shaw G, Liang YH, Subburaman P, Li Y, Wu Y, Yan H, Ji X. Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties. Bioorg Med Chem. 2012 Jan 1;20(1):47-57. Epub 2011 Nov 23. PMID:22169600 doi:10.1016/j.bmc.2011.11.032
  2. Shi G, Blaszczyk J, Ji X, Yan H. Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies. J Med Chem. 2001 Apr 26;44(9):1364-71. PMID:11311059

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