3sqe
Crystal structure of prethrombin-2 mutant S195A in the alternative formCrystal structure of prethrombin-2 mutant S195A in the alternative form
About this StructureAbout this Structure
3sqe is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Pozzi N, Chen Z, Zapata F, Pelc LA, Barranco-Medina S, Di Cera E. Crystal Structures of Prethrombin-2 Reveal Alternative Conformations under Identical Solution Conditions and the Mechanism of Zymogen Activation. Biochemistry. 2011 Nov 29;50(47):10195-202. Epub 2011 Nov 8. PMID:22049947 doi:10.1021/bi2015019
- ↑ Vijayalakshmi J, Padmanabhan KP, Mann KG, Tulinsky A. The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. Protein Sci. 1994 Dec;3(12):2254-71. PMID:7756983