1og5

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File:1og5.png

Template:STRUCTURE 1og5

STRUCTURE OF HUMAN CYTOCHROME P450 CYP2C9STRUCTURE OF HUMAN CYTOCHROME P450 CYP2C9

Template:ABSTRACT PUBMED 12861225

About this StructureAbout this Structure

1og5 is a 2 chain structure of Cytochrome P450 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2][xtra 3]

  1. Williams PA, Cosme J, Ward A, Angove HC, Matak Vinkovic D, Jhoti H. Crystal structure of human cytochrome P450 2C9 with bound warfarin. Nature. 2003 Jul 24;424(6947):464-8. Epub 2003 Jul 13. PMID:12861225 doi:http://dx.doi.org/10.1038/nature01862
  2. He XY, Shen J, Hu WY, Ding X, Lu AY, Hong JY. Identification of Val117 and Arg372 as critical amino acid residues for the activity difference between human CYP2A6 and CYP2A13 in coumarin 7-hydroxylation. Arch Biochem Biophys. 2004 Jul 15;427(2):143-53. PMID:15196988 doi:10.1016/j.abb.2004.03.016
  3. Thomas JH. Rapid birth-death evolution specific to xenobiotic cytochrome P450 genes in vertebrates. PLoS Genet. 2007 May 11;3(5):e67. Epub 2007 Mar 14. PMID:17500592 doi:10.1371/journal.pgen.0030067

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