3n0h
hDHFR double mutant Q35S/N64F Trimethoprim Binary ComplexhDHFR double mutant Q35S/N64F Trimethoprim Binary Complex
About this StructureAbout this Structure
3n0h is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Cody V, Pace J, Piraino J, Queener SF. Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase. J Struct Biol. 2011 Oct;176(1):52-9. Epub 2011 Jun 13. PMID:21684339 doi:10.1016/j.jsb.2011.06.001