3pe1
Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-4945Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-4945
About this StructureAbout this Structure
3pe1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Battistutta R, Cozza G, Pierre F, Papinutto E, Lolli G, Sarno S, O'Brien SE, Siddiqui-Jain A, Haddach M, Anderes K, Ryckman DM, Meggio F, Pinna LA. Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical stage for the treatment of cancer. Biochemistry. 2011 Aug 26. PMID:21870818 doi:10.1021/bi2008382
- ↑ Cozza G, Mazzorana M, Papinutto E, Bain J, Elliott M, di Maira G, Gianoncelli A, Pagano MA, Sarno S, Ruzzene M, Battistutta R, Meggio F, Moro S, Zagotto G, Pinna LA. Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2. Biochem J. 2009 Jul 15;421(3):387-95. PMID:19432557 doi:10.1042/BJ20090069