PhoP-PhoQ

Template:STRUCTURE 3bq8

PhoP-PhoQ is a two-component system which governs virulence and mediates the adptation to Mg+2-limiting conditions. PhoP is a response regulator and PhoQ is the inner membrane sensor. See details on PhoP in PhoP Regulatory Domain.

3D Structures of PhoP-PhoQ3D Structures of PhoP-PhoQ

PhoPPhoP

3r0j – MtPhoP – Mycobacterium tuberculosis
2pmu – MtPhoP DNA-binding domain
2pkx – EcPhoP regulatory domain (mutant) – Escherichia coli
2pl1 - EcPhoP regulatory domain (mutant) + BeF3
1mvo – PhoP N terminal – Bacillus subtilis

PhoQPhoQ

3cgy – StPhoQ catalytic domain + radicicol – Salmonella typhimurium
3cgz - StPhoQ catalytic domain
1yax - StPhoQ sensor domain (mutant)
3bq8 – EcPhoQ
3bqa – EcPhoQ (mutant)
1id0 – EcPhoQ kinase domain

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Andrew Brockfield, Alexander Berchansky