Template:STRUCTURE 3pp0

File:3pp0.png

Crystal Structure of the Kinase domain of Human HER2 (erbB2).Crystal Structure of the Kinase domain of Human HER2 (erbB2).

Template:ABSTRACT PUBMED 21454582

About this StructureAbout this Structure

3pp0 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Aertgeerts K, Skene R, Yano J, Sang BC, Zou H, Snell G, Jennings A, Iwamoto K, Habuka N, Hirokawa A, Ishikawa T, Tanaka T, Miki H, Ohta Y, Sogabe S. Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein. J Biol Chem. 2011 May 27;286(21):18756-65. Epub 2011 Mar 30. PMID:21454582 doi:10.1074/jbc.M110.206193

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OCA