Template:STRUCTURE 2ybp

File:2ybp.png

JMJD2A COMPLEXED WITH R-2-HYDROXYGLUTARATE AND HISTONE H3K36ME3 PEPTIDE (30-41)JMJD2A COMPLEXED WITH R-2-HYDROXYGLUTARATE AND HISTONE H3K36ME3 PEPTIDE (30-41)

Template:ABSTRACT PUBMED 21460794

About this StructureAbout this Structure

2ybp is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Chowdhury R, Yeoh KK, Tian YM, Hillringhaus L, Bagg EA, Rose NR, Leung IK, Li XS, Woon EC, Yang M, McDonough MA, King ON, Clifton IJ, Klose RJ, Claridge TD, Ratcliffe PJ, Schofield CJ, Kawamura A. The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Rep. 2011 May 1;12(5):463-9. Epub 2011 Apr 1. PMID:21460794 doi:10.1038/embor.2011.43

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OCA