3pj2
Crystal structure of BTK kinase domain complexed with 2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(4-fluoro-phenoxy)-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-oneCrystal structure of BTK kinase domain complexed with 2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(4-fluoro-phenoxy)-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
Template:ABSTRACT PUBMED 21280133
About this StructureAbout this Structure
3pj2 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Kuglstatter A, Wong A, Tsing S, Lee SW, Lou Y, Villasenor AG, Bradshaw JM, Shaw D, Barnett JW, Browner MF. Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures. Protein Sci. 2011 Feb;20(2):428-36. doi: 10.1002/pro.575. PMID:21280133 doi:10.1002/pro.575