3qk0
Crystal structure of PI3K-gamma in complex with benzothiazole 82Crystal structure of PI3K-gamma in complex with benzothiazole 82
About this StructureAbout this Structure
3qk0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ D'Angelo ND, Kim TS, Andrews K, Booker SK, Caenepeel S, Chen K, D'Amico D, Freeman D, Jiang J, Liu L, McCarter JD, San Miguel T, Mullady EL, Schrag M, Subramanian R, Tang J, Wahl RC, Wang L, Whittington DA, Wu T, Xi N, Xu Y, Yakowec P, Yang K, Zalameda LP, Zhang N, Hughes P, Norman MH. Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors. J Med Chem. 2011 Mar 24;54(6):1789-811. Epub 2011 Feb 18. PMID:21332118 doi:10.1021/jm1014605