2qo3

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File:2qo3.png

Template:STRUCTURE 2qo3

Crystal Structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthaseCrystal Structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase

Template:ABSTRACT PUBMED 17719492

About this StructureAbout this Structure

2qo3 is a 2 chain structure with sequence from Saccharopolyspora erythraea. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2][xtra 3][xtra 4]

  1. Tang Y, Chen AY, Kim CY, Cane DE, Khosla C. Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase. Chem Biol. 2007 Aug;14(8):931-43. PMID:17719492 doi:10.1016/j.chembiol.2007.07.012
  2. Chen AY, Cane DE, Khosla C. Structure-based dissociation of a type I polyketide synthase module. Chem Biol. 2007 Jul;14(7):784-92. PMID:17656315 doi:10.1016/j.chembiol.2007.05.015
  3. Tang Y, Kim CY, Mathews II, Cane DE, Khosla C. The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11124-9. Epub 2006 Jul 14. PMID:16844787
  4. Kim CY, Alekseyev VY, Chen AY, Tang Y, Cane DE, Khosla C. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase. Biochemistry. 2004 Nov 9;43(44):13892-8. PMID:15518537 doi:10.1021/bi048418n

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