2hd6
Crystal structure of the human carbonic anhydrase II in complex with a hypoxia-activatable sulfonamide.Crystal structure of the human carbonic anhydrase II in complex with a hypoxia-activatable sulfonamide.
Template:ABSTRACT PUBMED 16942027
About this StructureAbout this Structure
2hd6 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ De Simone G, Vitale RM, Di Fiore A, Pedone C, Scozzafava A, Montero JL, Winum JY, Supuran CT. Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX. J Med Chem. 2006 Sep 7;49(18):5544-51. PMID:16942027 doi:http://dx.doi.org/10.1021/jm060531j
- ↑ Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:http://dx.doi.org/10.1002/prot.340040406