2gni
PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077)PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077)
Template:ABSTRACT PUBMED 16699172
About this StructureAbout this Structure
2gni is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Bonn S, Herrero S, Breitenlechner CB, Erlbruch A, Lehmann W, Engh RA, Gassel M, Bossemeyer D. Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity. J Biol Chem. 2006 Aug 25;281(34):24818-30. Epub 2006 May 12. PMID:16699172 doi:10.1074/jbc.M512374200
- ↑ Breitenlechner C, Gassel M, Hidaka H, Kinzel V, Huber R, Engh RA, Bossemeyer D. Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure. 2003 Dec;11(12):1595-607. PMID:14656443