3q4c
Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292
About this StructureAbout this Structure
3q4c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry. 2009 Jun 16;48(23):5187-98. PMID:19371126 doi:10.1021/bi802067u