1ql7

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File:1ql7.png

Template:STRUCTURE 1ql7

FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSINFACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN

About this StructureAbout this Structure

1ql7 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2][xtra 3]

  1. Stubbs MT, Reyda S, Dullweber F, Moller M, Klebe G, Dorsch D, Mederski WW, Wurziger H. pH-dependent binding modes observed in trypsin crystals: lessons for structure-based drug design. Chembiochem. 2002 Mar 1;3(2-3):246-9. PMID:11921406
  2. Renatus M, Bode W, Huber R, Sturzebecher J, Stubbs MT. Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase. J Med Chem. 1998 Dec 31;41(27):5445-56. PMID:9876114 doi:10.1021/jm981068g
  3. Stubbs MT, Huber R, Bode W. Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. FEBS Lett. 1995 Nov 13;375(1-2):103-7. PMID:7498454

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