1ohy

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File:1ohy.png

Template:STRUCTURE 1ohy

4-AMINOBUTYRATE-AMINOTRANSFERASE INACTIVATED BY GAMMA-ETHYNYL GABA4-AMINOBUTYRATE-AMINOTRANSFERASE INACTIVATED BY GAMMA-ETHYNYL GABA

Template:ABSTRACT PUBMED 14534310

About this StructureAbout this Structure

1ohy is a 4 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. Storici P, De Biase D, Bossa F, Bruno S, Mozzarelli A, Peneff C, Silverman RB, Schirmer T. Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin. J Biol Chem. 2004 Jan 2;279(1):363-73. Epub 2003 Oct 8. PMID:14534310 doi:10.1074/jbc.M305884200
  2. Storici P, Capitani G, De Biase D, Moser M, John RA, Jansonius JN, Schirmer T. Crystal structure of GABA-aminotransferase, a target for antiepileptic drug therapy. Biochemistry. 1999 Jul 6;38(27):8628-34. PMID:10393538 doi:10.1021/bi990478j

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