Sheets in Proteins

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A β-pleated sheet contains multiple peptide strands that are positioned adjacent to one another (such as the one on the right). The planes of the are formed by the planes of the peptide bond. The alpha carbons of the peptide chain are at the valleys and peaks of the pleats. The peptides are (blue amino end changing to red carboxy end) to show that the adjacent peptides are running in opposite directions making the sheet antiparallel. Another way of detecting the is by displaying as cartoon. The adjacent chains align so that are formed between the imino hydrogens of one chain and the carbonyl oxygens of an adjacent chain. Psi and phi values that permit this alignment in antiparallel sheets have of 1350 and -1390, respectively. The mean values for a parallel sheet are . Twisted sheet is another type of β-sheet. Unlike the of sheets the valleys and the peaks of a twisted sheet do not fall on parallel lines.

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Karl Oberholser, Angel Herraez, Jaime Prilusky, Eric Martz, Karsten Theis